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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

Sallie Permar, HIVR4P 2021: Pediatric HIV acquisition, Immunity and New Prevention Strategies

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Published Online: Mar 23rd 2021

We were delighted to have an opportunity to speak with Sallie Permar (Weill Cornell Medicine, New York City, NY, USA) to discuss her work in HIV immunity and prevention strategies.

The abstract entitled: ‘Mother and child: HIV acquisition, immunity and new prevention strategies’ (PL02.01) was presented at the HIVR4P Virtual Conference 2021, 28 January 2021.

Questions:

  1. What is known about passive immunization to HIV with broadly neutralizing antibodies (bNAbs)? (0:05)
  2. Could you tell us a little about new HIV vaccine approaches using HIV-1 envelope (Env) immunogens? (1:48)
  3. What clinical evidence supports the use of CoBG505 SOSIP.664 trimers? (3:14)
  4. What is the rationale for multidose vaccination and when should these doses be administered? (4:42)

Disclosures: Sallie Permar as nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media.

Filmed in coverage of the HIVR4P Virtual Conference 2021.

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