Joseph Domachowske: Phase III MELODY and phase IIb trials investigating nirsevimab for the treatment of respiratory syncytial virus

Learn about the integration of the latest data in antiretroviral management of HIV, challenges clinicians may face when adopting new strategies and updates from the Conference of Retroviruses and Opportunistic Infections (CROI) 2024 are reported here by Dr Eric Daar, Division of HIV Medicine, Harbor-UCLA Medical Center, Atlanta, GA, USA.

Antiretroviral therapy (ART) effectively manages HIV by suppressing viral replication. It's crucial for healthcare professionals (HCPs) to keep abreast of ART updates for optimal patient care. Dr. Eric Daar, Harbor-UCLA Medical Center, reports on CROI 2024, underscoring the efficacy of long-acting injectable (LAI) therapies in trials like CARES, MOCHA, and LATITUDE. The findings support LAI therapy's potential for global HIV treatment programs, including in resource-limited settings like sub-Saharan Africa.

DANFLU-1 was an open-label, active-controlled, individually randomized trial conducted in Denmark during the 2021/2022 northern hemisphere influenza season. Dr Niklas Dyrby Johansen (University of Copenhagen Copenhagen, Denmark) discusses the post-hoc analysis from DANFLU-1 which investigated the effects of high-dose quadrivalent influenza vaccine (QIV-HD) vs standard-dose quadrivalent influenza vaccine (QIV-SD). The abstract ‘Relative effectiveness of high-dose […]