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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

Ethel Weld, HIVR4P 2021: Long-acting Cabotegravir in HIV Prophylaxis (Part 2)

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Published Online: Mar 25th 2021

We had the pleasure of meeting with Ethel Weld (Johns Hopkins University School of Medicine, Baltimore, MD, US) to discuss long acting cabotegravir in HIV prophylaxis.

Part 1 of the discussion can be viewed here.

The abstract entitled: ‘Distribution of long-acting (LA) cabotegravir (CAB) in plasma, mucosal tissues, and associated fluids after a single ultrasound-guided intramuscular (IM) injection in healthy adult participants’ (OA04.03) was presented at the HIVR4P Virtual Conference 2021, 27 January 2021.

Questions:

  1. Could you give us an overview of the study and its findings? (0:19)
  2. Why was it important to evaluate CAB LA levels in plasma, mucosal tissue and associated fluids? (1:29)
  3. How can the distribution of CAB help inform future studies? (6:18)

Disclosures: Ethel Weld has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed in coverage of the HIVR4P 2021 Virtual Meeting. 

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