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Aqsa Jawaid Siddiqui, Aamir Sikandar Kazi, Ghina Shamim Shamsi

Tuberculous mastitis (TM) is a rare chronic granulomatous disease predominantly caused by Mycobacterium tuberculosis.1 TM accounts for less than 0.1% of all breast diseases worldwide, whereas it is more common in endemic regions (3–4.5%).2,3 TM is more prevalent in the reproductive age group, especially during the lactation period, when patients are more susceptible since the […]

Richard Sterling, ACTHIV 2022: NAFLD and NASH in people with HIV – Prevalence, pathogenesis, biomarkers, and research priorities

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Published Online: May 18th 2022

The prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in people with HIV is relatively common. Dr Richard Sterling (Virginia Commonwealth University, Richmond, VA, USA) joins touchINFECTIOUS DISEASES to discuss the pathogenesis and factors associated with the development of fatty liver in people with HIV, biomarkers proven effective for NAFLD in HIV, and the research priorities in HIV-associated NAFLD.

The presentation entitled: ‘Diagnosis and Epidemiology of NAFLD/NASH in HIV–Unique Opportunities and Challenges’ was presented at the American Conference for the Treatment of HIV (ACTHIV), May 5-7, 2022.

Questions:

  1. Could you give us a brief overview of the prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in people with HIV?
  2. What is known about the pathogenesis of NAFLD in HIV?
  3. What factors are associated with the development of fatty liver in people with HIV?
  4. What biomarkers have proven effective for NAFLD in HIV?
  5. What are the research priorities in HIV-associated NAFLD and what studies are ongoing?

Disclosures: Richard Sterling receives or has received grant/research Support from Abbie, Abbott, Gilead, and Roche.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of ACTHIV 2022

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