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Invasive fungal infections such as candidiasis and aspergillosis are becoming more common with increasing global temperatures and more frequent natural disasters, emphasizing the importance of antifungal readiness. Understanding the roles of specific antifungal classes and when to escalate treatment is key to appropriate therapeutic decision-making. In this Fungi Now series, learn how the risk of invasive fungal infections is increasing and practical management strategies for key pathogens.Â
After watching these videos and reviewing the related references, participants should be better able to:
It is with great pleasure that I introduce Fungi Now.Â
Fungi Now continues the tradition of the in-person CARE meetings which provided education and cutting-edge updates in mycology for clinicians from a variety of specialties over the past 16 years.
Fungi Now recognizes the way we consume education has changed and takes the form of a targeted series of short discussions of new concepts and publications by leading experts.
Many thanks to the CARE steering committee, Prof. Peter Donnelly, Prof. Malcolm Richardson, Prof. Johan Maertens and Prof. Patricia Munoz for their dedication to and guidance of the CARE meetings and to Gilead for their continued commitment to education.
I hope you enjoy this new approach.
Professor Monica Slavin
CARE steering committee
Prof. Martin Hoenigl is an Associate Professor for Translational Mycology at the Division of Infectious Diseases, Medical University of Graz, Austria. His research interests focus on clinical mycology, including fungal diagnostics, host-fungal pathogen interactions, and pharmacology of antifungal drugs. He has worked in mycology for over 15 years, and has published over 350 scientific papers. He is the past president of the European Confederation of Medical Mycology (ECMM), and serves an editor for several leading mycology journals.
Received research funding from Basilea, Gilead, Elion, F2G, GSK, IMMY, Pulmocide, Melinta, Mundipharma, Pharmaholdings, Shionogi and Scynexis.
Dr Souha Kanj is a Professor of Medicine at the American University of Beirut Medical Center (AUBMC), and Chair of the Infection Control Program, co-Chair of the Antimicrobial Stewardship Program, and Consulting Professor at Duke University Medical Center. Her research focuses on nosocomial infections, antimicrobial resistance and stewardship, nosocomial infections, infection control, ID during wars, and fungal infections. She has co-authored over 325 peer-reviewed articles, book chapters, and UpToDate® cards. She serves as an advisory member for WHO programs in infection control, antimicrobial resistance, priority pathogens, diagnostic stewardship, COVID-19, and fungal infections.
Honoraria for speaker and advisory board member for Menarini, MSD, Pfizer, Hikma, Gilead. Author of UpTodate cards. Participated in ECMM guidelines.
Prof. Johan Maertens is a hematologist and Associate Professor at University Hospitals Leuven, Belgium. His work focuses on invasive fungal diseases, particularly in immunocompromised patients. He has authored more than 450 scientific publications, is a founding member and current chair of the European Conference on Infections in Leukaemia (ECIL), a past chair of the EORTC Infectious Diseases Group, and a Fellow of the European Confederation of Medical Mycology.
Grants or contracts from F2G, Gilead, MSD, Mundipharma, Pfizer. Consulting fees from Abbvie, Servier, Basilea, Takeda, Daiichi Sankyo, Cidara, Asahi Kasei Pharma Corporation, Gilead, Elion Therapeutics, Novo Nordisk, MedPace, Menarini, Mundipharma, Pfizer, Scynexis, Shionogi, Biosergen and Octapharma. Speaker and lecture honoraria from Takeda, Abbvie, Gilead, Medscape/WebMD, MSD, Mundipharma, Pfizer, Shionogi. Payment for expert testimony from Cidara, Mundipharma and F2G.
Prof. George Dimopoulos is a Professor of Pulmonary and Critical Care Medicine at the National and Kapodistrian University of Athens, Head of the 3rd University Department of Critical Care at EVGENIDIO Hospital and Consultant in Critical Care in Therapeutic Clinic at ALEXANDRA Hospital, all in Greece. He has authored more than 300 scientific papers and reviews and contributed to more than 70 book chapters. He is a former chair of the Respiratory Infections Assembly of the European Respiratory Society (ERS) and Infection Section of the European Society of Intensive Care Medicine (ESICM), a past Education Officer of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Critically Ill Patients, and a Fellow of the European Confederation of Medical Mycology (ECMM).
Advisory boards: Menarini, Gilead, MSD and VERMA Drugs.
Prof. Ignacio Martin-Loeches is a Professor of Intensive Care Medicine at Trinity College Dublin and Consultant at St James’s Hospital, Ireland. He specializes in severe infection, sepsis, and ICU acquired respiratory disease and has authored more than 600 peer reviewed publications, including on critical care guidelines and translational infection science. He serves as Chair of the Critical Care Group at the European Respiratory Society and Chair of Research at the European Society of Intensive Care Medicine, currently leads the ERS European Network for ICU-related Respiratory Infections, and is a former Steering Committee member of the Surviving Sepsis Campaign.
Received funding from Gilead, MSD, Mundipharma, Pfizer and Thermofisher.
Key publication from Episode 1:
Seidel D, Wurster S, Jenks JD, Sati H, Gangneux JP, Egger M, et al. Impact of climate change and natural disasters on fungal infections. Lancet Microbe. 2024;5(6):e594–e605.
Key publication from Episode 2 (international guidelines on managing candidiasis):Â
Cornely OA, Sprute R, Bassetti M, Chen SC, Groll AH, Kurzai O, et al. Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis. 2025;25(5):e280–e93.
Key publication from Episode 4:Â
Akinosoglou K, Rigopoulos EA, Papageorgiou D, Schinas G, Polyzou E, Dimopoulou E, et al. Amphotericin B in the Era of New Antifungals: Where Will It Stand? J Fungi (Basel). 2024;10(4).
Key publication from Episode 5:Â
Maseda E, MartÃn-Loeches I, Zaragoza R, Pemán J, Fortún J, Grau S, et al. Critical appraisal beyond clinical guidelines for intraabdominal candidiasis. Crit Care. 2023;27(1):382.
For information on global Candida auris reporting:
Friedman DZP, Schwartz IS. Emerging Fungal Infections: New Patients, New Patterns, and New Pathogens. J Fungi (Basel). 2019 Jul 20;5(3):67.
For more on the impact of higher temperatures and low rainfall on Dimorphic fungi see:Â
George ME, Gaitor TT, Cluck DB, Henao-MartÃnez AF, Sells NR, Chastain DB. The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies. Ther Adv Infect Dis. 2025;12:20499361251313841.
For the international guidelines on managing Aspergillus diseases:
Ullmann AJ, Aguado JM, Arikan-Akdagli S, Denning DW, Groll AH, Lagrou K, et al. Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline. Clin Microbiol Infect. 2018;24 Suppl 1:e1-e38.
For the international guidelines on managing mucormycosis diseases:Â
Cornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, et al. Mucormycosis ECMM MSG Global Guideline Writing Group. Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium. Lancet Infect Dis. 2019;19(12):e405-e421.
This activity is funded by Gilead Sciences, Inc. and is intended for healthcare professionals only.
The content of this activity is non-promotional and aims to provide an update on the most relevant recent publications on invasive fungal infections.
Gilead Sciences, Inc. provided financial support and content, and has had input into the detailed project scope. This activity is provided by Touch Medical Communications (TMC) for touchINFECTIOUS DISEASES.
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This activity is funded by Gilead Sciences, Inc. and is intended for healthcare professionals only.Â
The content of this activity is non-promotional and aims to provide an update on the most relevant recent publications on invasive fungal infections.
Gilead Sciences, Inc. provided financial support and content, and has had input into the detailed project scope. This activity is provided by Touch Medical Communications (TMC) for touchINFECTIOUS DISEASES.
Gilead medicinal products may be mentioned in the scientific discussion. Please refer to the locally approved prescribing information for AmBisome Liposomal (Amphotericin B), as product information may differ between countries.
Adverse events should be reported to Gilead at Safety_FC@gilead.com and/or through your national reporting system.
TMC accepts no responsibility for errors or omissions.
The views and opinions expressed are those of the faculty and do not necessarily reflect those of any sponsor.
GFM-UNB-2063
Date of preparation: January 2026
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