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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

Kelly Dooley, ECCMID 2021: New drugs and Regimens for Treating Drug-resistant Tuberculosis

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Published Online: Aug 23rd 2021

We met with Kelly Dooley (Johns Hopkins University School of Medicine, Baltimore, MD, USA) to discuss the new drugs and developing treatment regimens for drug-resistant tuberculosis.

The session entitled: ‘New drugs and new regimens for treating drug-resistant tuberculosis’ was presented at the 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID).

Questions:

  1. What are the most important second wave drugs for the treatment of tuberculosis, and what advantages do they offer over older drugs? (0:25)
  2. Could you tell us a little about the NixTB clinical trial, its findings and their impact on clinical practice? (2:48)
  3. What biomarkers seem useful in the development of drugs and regimens? (5:39)

Disclosures:

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed in coverage of the 31st ECCMID Congress 2021.

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