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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

Kelly Dooley, ECCMID 2021: Challenges in Developing New Treatments for Drug-resistant Tuberculosis

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Published Online: Aug 23rd 2021

It was a pleasure to meet with Kelly Dooley (Johns Hopkins University School of Medicine, Baltimore, MD, USA) to discuss the major challenges to developing new treatment regimens for drug-resistant tuberculosis.

The session entitled: ‘New drugs and new regimens for treating drug-resistant tuberculosis’ was presented at the 31st European Congress of Clinical Microbiology & Infectious Diseases (ECCMID).

Questions:

  1. Could you give us a brief overview of drug-resistant tuberculosis, its global burden and the urgency of the need for new treatments? (0:25)
  2. What are the major challenges to developing new treatment regimens and how may these be overcome? (1:50)
  3. What are the challenges in treating tuberculosis in HIV-positive people? (3:19)
  4. What are the recommended treatment regimens for multi drug resistant tuberculosis? (4:50)

Disclosures: Kelly Dooley has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed as a highlight of ECCMID , Virtual 2021.

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