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Bacterial and Fungal Infections, HIV

David Lawrence, IAS 2021: Phase 3 AMBITION Trial Results

Published Online: August 17th 2021

We had the pleasure to meet with David Lawrence (London School of Hygiene and Tropical Medicine, London, UK) to discuss the phase 3 AMBITION trial results investigating liposomal amphotericin for treatment of HIV-associated Cryptococcal Meningitis.

The abstract entitled: ‘Single high-dose liposomal amphotericin based regimen for treatment of HIV-associated Cryptococcal Meningitis: results of the phase-3 Ambition-cm Randomised Trial’ was presented at IAS 2021 – the 11th International AIDS Society Conference on HIV Science (Virtual).

Questions:

  1. What were the aims of the AMBITION study?
  2. Could you tell us a little about the study design, eligibility criteria and outcome measures?
  3. How well were the primary and secondary outcome measures achieved?

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

Filmed in coverage of IAS 2021 Virtual.

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