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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

The Hecolin® vaccine in the prevention of hepatitis E: Iza Ciglenecki, EASL 2023

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Published Online: Jul 19th 2023

A three-dose recombinant vaccine (Hecolin®) against hepatitis E has been licensed in China since 2011. We caught up with Dr Iza Ciglenecki (Médecins Sans Frontières, Geneva, Switzerland) to discuss the prognosis and treatment paradigm for hepatitis E, the challenges associated with optimizing hepatitis E vaccine efficacy and reducing the burden of disease, and what is known about the efficacy of the Hecolin® vaccine in the prevention of hepatitis E.

The abstract ‘The first mass reactive vaccination campaign against hepatitis E in Bentiu, South Sudan: feasibility, vaccination coverage and two-dose vaccine effectiveness‘ was presented at EASL 2023, 21–24 June 2023, Vienna, Austria.

Questions:

  1. What is the prognosis and treatment paradigm for hepatitis E? (0:20)
  2. What are the challenges associated with optimizing hepatitis E vaccine efficacy and reducing the burden of disease? (1:01)
  3. What is already known about the efficacy of the Hecolin® vaccine in the prevention of hepatitis E? (2:03)

Disclosures: Iza Ciglenecki has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Atiya Henry.

Filmed in coverage of EASL 2023

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