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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

Kevin Garey, IDWeek 2021: Health-related Quality of Life Findings from the ECOSPOR Phase 3 Trial

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Published Online: Oct 22nd 2021

It was a pleasure to meet with Prof. Kevin Garey (University of Houston College of Pharmacy, Houston, TX, USA) to discuss the results from the ECOSPOR phase 3 trial, and how SER-109 impacts patients’ health-related quality of life. Watch Part 1 of this interview here.

The abstract entitled: ‘The Impact of Investigational Purified Microbiome Therapeutic SER-109 on Health-Related Quality of Life (HRQoL) of Patients with Recurrent Clostridioides difficile Infection (rCDI) in ECOSPOR III, a Placebo-Controlled Clinical Trial’ was presented at IDWeek 2021 (Virtual), 28 September – 3 October 2021.

Questions:

  1. What is SER-109 and how is it manufactured? (0:13)
  2. What have we learned from the ECOSPOR III study about the impact of SER-109 on recurrent C difficile infections? (0:45)
  3. What were the findings of the health-related quality of life analysis? (1:50)
  4. What questions remain unanswered and what future studies are planned? (3:26)

Disclosures: Kevin Garey has research grants paid to his university from Seres Therapeutics.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

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