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A double-stranded DNA virus of the Orthopoxvirus family, mpox (formerly monkeypox), continues to infect people daily, following the 2022 global outbreak.1 Two clades (clade 1 and clade 2) have been identified, with the 2022 outbreak caused by a subclade of clade 2, referred to as clade 2b.2 Comparatively, clade 1 leads to a more severe disease state and greater […]

Jeffrey Strich: Phase 2 Trial Results Investigating Fostamatinib for the treatment of COVID-19

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Published Online: Sep 24th 2021

It was a great pleasure to meet with Jeffrey Strich (National Institutes of Health Clinical Center, Bethesda, MD, USA) to discuss the findings from a recent phase 2 study investigating fostamatinib for the treatment of hospitalized adults with COVID-19.

Useful Resources:

Published data available here: Fostamatinib for the treatment of hospitalized adults with COVID-19 A randomized trial

Questions:

  1. What is the rationale for adding fostamatinib to standard of care in hospitalised COVID-19 patients? (0:15)
  2. Could you tell us a little about the aims and design of your recent Phase II study? (3:30)
  3. What were the efficacy and safety findings of the study? (5:04)
  4. What were the conclusions of the investigators? (7:17)
  5. What questions remain unanswered and what further studies are planned? (8:21)

Disclosures: Jeffrey Strich has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Katey Gabrysch.

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